3L9J
Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | TNFalpha | polymer | 134 | 15314.2 | 1 | Pfam (PF00059) UniProt (by SIFTS) (P05452) | Homo sapiens (human) | |
| 2 | B (T) | Tumor necrosis factor, soluble form | polymer | 149 | 16497.7 | 1 | UniProt (P01375) Pfam (PF00229) | Homo sapiens (human) | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin |
| 3 | C (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (C, T) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31811.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 31836.2 |
