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3L9J

Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex

Functional Information from GO Data
ChainGOidnamespacecontents
T0005164molecular_functiontumor necrosis factor receptor binding
T0006955biological_processimmune response
T0016020cellular_componentmembrane
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG C 497
ChainResidue
CHOH202
CHOH210
CHOH221
CHOH245
CHOH246
CHOH251

Functional Information from PROSITE/UniProt
site_idPS00251
Number of Residues17
DetailsTHD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvVPsEGLYLIysQVlF
ChainResidueDetails
TLEU48-PHE64

224004

PDB entries from 2024-08-21

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