3L2V
Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and MK0518 (Raltegravir)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Integrase | polymer | 395 | 44456.7 | 2 | UniProt (P14350) Pfam (PF17921) Pfam (PF00665) Pfam (PF18103) In PDB | Human spumaretrovirus (SFVcpz(hu)) | IN, p42In |
| 2 | C | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3' | polymer | 19 | 5864.8 | 1 | |||
| 3 | D | 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3' | polymer | 17 | 5163.4 | 1 | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 6 | A | AMMONIUM ION | non-polymer | 18.0 | 1 | Chemie (NH4) | |||
| 7 | A | N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide | non-polymer | 444.4 | 1 | Chemie (RLT) | |||
| 8 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) |
Sequence modifications
A, B: 1 - 392 (UniProt: P14350)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 217 | Gly 968 | variant |
| Gly 218 | Ser 969 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 99941.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1061.1 | |
| All* | Total formula weight | 101002.7 |
