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3L26

Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Polymerase cofactor VP35polymer12914210.52UniProt (Q05127)
Pfam (PF02097)
Zaire ebolavirus (ZEBOV)
2C
(C)
RNA (5'-R(*CP*GP*CP*AP*UP*GP*CP*G)-3')polymer82541.61
3D, E, I, J, M
(A, B, C)
MAGNESIUM IONnon-polymer24.35Chemie (MG)
4F, G, H, K, L
(A, B)
CHLORIDE IONnon-polymer35.55Chemie (CL)
5N, O, P
(A, B, C)
waterwater18.0233Chemie (HOH)
Sequence modifications
A, B: 215 - 340 (UniProt: Q05127)
PDBExternal DatabaseDetails
Gly 212-expression tag
His 213-expression tag
Met 214-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight30962.6
Non-Polymers*Number of molecules10
Total formula weight298.8
All*Total formula weight31261.4
*Water molecules are not included.

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PDB entries from 2025-12-24

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