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3L26

Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA

Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG A 1
ChainResidue
AHOH63
AHOH122
AHOH123
ALEU232
APRO233
AGLY234
APHE235

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 4
ChainResidue
CHOH59
CHOH69
AARG305
BHOH109

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CL A 341
ChainResidue
APHE235
AARG305
BPRO316

site_idAC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE CL A 3
ChainResidue
AHOH83
AHOH174
AARG300

site_idAC5
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL A 342
ChainResidue
AHIS296

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG B 3
ChainResidue
BHOH104
BHOH104
BPRO315
BPRO315
BPRO316
BPRO316

site_idAC7
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG B 5
ChainResidue
AGLY333
ATHR335
BHOH71
BHOH164
BLEU232
BPRO233
BGLY234

site_idAC8
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CL B 2
ChainResidue
AALA291
BPRO304

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG C 9
ChainResidue
CU5
CU5
CHOH25
CHOH25
CHOH98
CHOH98

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine; by host => ECO:0000269|PubMed:31562565
ChainResidueDetails
ASER310
BSER310

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine; by host => ECO:0000269|PubMed:31562565, ECO:0000269|PubMed:31694758
ChainResidueDetails
ASER317
BSER317

site_idSWS_FT_FI3
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:28679761, ECO:0000269|PubMed:35533195
ChainResidueDetails
ALYS309
BLYS309

226707

PDB entries from 2024-10-30

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