3L26
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 1 |
| Chain | Residue |
| A | HOH63 |
| A | HOH122 |
| A | HOH123 |
| A | LEU232 |
| A | PRO233 |
| A | GLY234 |
| A | PHE235 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 4 |
| Chain | Residue |
| C | HOH59 |
| C | HOH69 |
| A | ARG305 |
| B | HOH109 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 341 |
| Chain | Residue |
| A | PHE235 |
| A | ARG305 |
| B | PRO316 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 3 |
| Chain | Residue |
| A | HOH83 |
| A | HOH174 |
| A | ARG300 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 342 |
| Chain | Residue |
| A | HIS296 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 3 |
| Chain | Residue |
| B | HOH104 |
| B | HOH104 |
| B | PRO315 |
| B | PRO315 |
| B | PRO316 |
| B | PRO316 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 5 |
| Chain | Residue |
| A | GLY333 |
| A | THR335 |
| B | HOH71 |
| B | HOH164 |
| B | LEU232 |
| B | PRO233 |
| B | GLY234 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 2 |
| Chain | Residue |
| A | ALA291 |
| B | PRO304 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 9 |
| Chain | Residue |
| C | U5 |
| C | U5 |
| C | HOH25 |
| C | HOH25 |
| C | HOH98 |
| C | HOH98 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"PubMed","id":"31562565","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"PubMed","id":"31562565","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31694758","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"28679761","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35533195","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
