3KWW
Crystal structure of the 'restriction triad' mutant of HLA B*3508, beta-2-microglobulin and EBV peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HLA class I histocompatibility antigen, B-35 alpha chain | polymer | 276 | 31840.2 | 1 | UniProt (P30685) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) In PDB | Homo sapiens (human) | MHC class I antigen B*35 |
| 2 | B | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C | peptide from Trans-activator protein BZLF1 | polymer | 13 | 1426.6 | 1 | UniProt (P03206) In PDB | EB1, Protein zebra | |
| 4 | A | ACETIC ACID | non-polymer | 60.1 | 7 | Chemie (ACY) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | A, B, C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 8 | Chemie (PEG) | |||
| 7 | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P30685)
| PDB | External Database | Details |
|---|---|---|
| Ala 65 | Gln 89 | engineered mutation |
| Ala 69 | Thr 93 | engineered mutation |
| Ala 155 | Gln 179 | engineered mutation |
| Arg 156 | Leu 180 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45014.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1361.4 | |
| All* | Total formula weight | 46376.3 |
