3KTM
Structure of the Heparin-induced E1-Dimer of the Amyloid Precursor Protein (APP)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Amyloid beta A4 protein | polymer | 191 | 21762.1 | 8 | UniProt (P05067) Pfam (PF02177) Pfam (PF12924) In PDB | Homo sapiens (human) | Alzheimer disease amyloid protein, ABPP, APP |
2 | A, B, C, D, E... | (3R)-butane-1,3-diol | non-polymer | 90.1 | 8 | Chemie (BU4) | |||
3 | B, C, D, E, H | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
4 | B, C, E, H | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
5 | water | water | 18.0 | 282 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 18 - 190 (UniProt: P05067)
PDB | External Database | Details |
---|---|---|
Met 17 | - | initiating methionine |
Ile 191 | - | expression tag |
Glu 192 | - | expression tag |
Gly 193 | - | expression tag |
Arg 194 | - | expression tag |
Lys 195 | - | expression tag |
Leu 196 | - | expression tag |
Ala 197 | - | expression tag |
Ala 198 | - | expression tag |
Ala 199 | - | expression tag |
Leu 200 | - | expression tag |
Glu 201 | - | expression tag |
His 202 | - | expression tag |
His 203 | - | expression tag |
His 204 | - | expression tag |
His 205 | - | expression tag |
His 206 | - | expression tag |
His 207 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 174096.6 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 1437.5 | |
All* | Total formula weight | 175534.1 |