3KS8

Crystal structure of Reston ebolavirus VP35 RNA binding domain in complex with 18bp dsRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (E)	5'-R(*AP*GP*AP*AP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*A)-3'	polymer	18	6056.7	1
2	B (F)	5'-R(*UP*CP*CP*UP*CP*CP*CP*UP*CP*CP*CP*UP*CP*CP*UP*UP*CP*U)-3'	polymer	18	5455.2	1
3	C, D, E, F (A, B, C, D)	Polymerase cofactor VP35	polymer	184	20569.4	4	UniProt (Q8JPY0) Pfam (PF02097)	Reston ebolavirus (REBOV)
4	G, H, I, J, K... (E, F, A, B, C...)	water	water		18.0	150	Chemie (HOH)

Sequence modifications

A, B, C, D: 160 - 329 (UniProt: Q8JPY0)

PDB	External Database	Details
Met 146	-	expression tag
Ala 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
Val 154	-	expression tag
Asp 155	-	expression tag
Asp 156	-	expression tag
Asp 157	-	expression tag
Asp 158	-	expression tag
Lys 159	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	93789.6
All*	Total formula weight	93789.6

*Water molecules are not included.