3KFL

Leishmania major methionyl-tRNA synthetase in complex with methionyladenylate and pyrophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Methionyl-tRNA synthetase	polymer	564	63984.8	1	UniProt (Q4QCD2) Pfam (PF09334) Pfam (PF19303)	Leishmania major
2	B (A)	[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate	non-polymer		478.4	1	Chemie (ME8)
3	C (A)	PYROPHOSPHATE 2-	non-polymer		176.0	1	Chemie (POP)
4	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	E (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6	F, G, H, I, J... (A)	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
7	M, N, O, P (A)	FORMIC ACID	non-polymer		46.0	4	Chemie (FMT)
8	Q (A)	water	water		18.0	217	Chemie (HOH)

Sequence modifications

A: 206 - 747 (UniProt: Q4QCD2)

PDB	External Database	Details
Met -21	-	expression tag
Ala -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Gly -12	-	expression tag
Thr -11	-	expression tag
Leu -10	-	expression tag
Glu -9	-	expression tag
Ala -8	-	expression tag
Gln -7	-	expression tag
Thr -6	-	expression tag
Gln -5	-	expression tag
Gly -4	-	expression tag
Pro -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63984.8
Non-Polymers*	Number of molecules	15
	Total formula weight	1362.7
All*	Total formula weight	65347.5

*Water molecules are not included.