3KFD
Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H (A, B, C, D) | Transforming growth factor beta-1 | polymer | 112 | 12809.8 | 4 | UniProt (P01137) Pfam (PF00019) | Homo sapiens (human) | TGF-beta-1, Latency-associated peptide, LAP |
| 2 | C, D, I, J (E, F, G, H) | TGF-beta receptor type-2 | polymer | 116 | 13225.0 | 4 | UniProt (P37173) Pfam (PF08917) | Homo sapiens (human) | Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TGF-beta type II receptor, TbetaR-II, TGFR-2 |
| 3 | E, F, K, L (I, J, K, L) | TGF-beta receptor type-1 | polymer | 85 | 9330.7 | 4 | UniProt (P36897) Pfam (PF01064) | Homo sapiens (human) | Transforming growth factor-beta receptor type I, TGF-beta receptor type I, TGF-beta type I receptor, TbetaR-I, TGFR-1, Serine/threonine-protein kinase receptor R4, SKR4, Activin receptor-like kinase 5, ALK-5 |
| 4 | M, N, O, P, Q... (A, B, E, F, I...) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 141462.2 | |
| All* | Total formula weight | 141462.2 |
