3KFD

Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008083	molecular_function	growth factor activity
B	0005576	cellular_component	extracellular region
B	0008083	molecular_function	growth factor activity
C	0005576	cellular_component	extracellular region
C	0008083	molecular_function	growth factor activity
D	0005576	cellular_component	extracellular region
D	0008083	molecular_function	growth factor activity
E	0005026	molecular_function	transforming growth factor beta receptor activity, type II
E	0005524	molecular_function	ATP binding
E	0006468	biological_process	protein phosphorylation
E	0016020	cellular_component	membrane
E	0046872	molecular_function	metal ion binding
F	0005026	molecular_function	transforming growth factor beta receptor activity, type II
F	0005524	molecular_function	ATP binding
F	0006468	biological_process	protein phosphorylation
F	0016020	cellular_component	membrane
F	0046872	molecular_function	metal ion binding
G	0005026	molecular_function	transforming growth factor beta receptor activity, type II
G	0005524	molecular_function	ATP binding
G	0006468	biological_process	protein phosphorylation
G	0016020	cellular_component	membrane
G	0046872	molecular_function	metal ion binding
H	0005026	molecular_function	transforming growth factor beta receptor activity, type II
H	0005524	molecular_function	ATP binding
H	0006468	biological_process	protein phosphorylation
H	0016020	cellular_component	membrane
H	0046872	molecular_function	metal ion binding
I	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
I	0016020	cellular_component	membrane
J	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
J	0016020	cellular_component	membrane
K	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
K	0016020	cellular_component	membrane
L	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
L	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IhePkgYhanfClGpC

Chain	Residue	Details
A	ILE33-CYS48

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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