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3K6N

Crystal structure of the S225E mutant Kir3.1 cytoplasmic pore domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
G protein-activated inward rectifier potassium channel 1polymer20723615.91UniProt (P63250)
Pfam (PF01007)
Pfam (PF17655)
Mus musculus (mouse)GIRK1, Potassium channel, inwardly rectifying subfamily J member 3, Inward rectifier K(+) channel Kir3.1
2B, C, D, E, F
(A)
SODIUM IONnon-polymer23.05Chemie (NA)
3G
(A)
waterwater18.0180Chemie (HOH)
Sequence modifications
A: 41 - 63 (UniProt: P63250)
PDBExternal DatabaseDetails
Gly 39-expression tag
Ser 40-expression tag
A: 190 - 371 (UniProt: P63250)
PDBExternal DatabaseDetails
Glu 225Ser 225engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23615.9
Non-Polymers*Number of molecules5
Total formula weight114.9
All*Total formula weight23730.9
*Water molecules are not included.

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PDB entries from 2025-12-24

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