3K05
The crystal structure of MDC1 BRCT T2067D in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Mediator of DNA damage checkpoint protein 1 | polymer | 200 | 21856.3 | 2 | UniProt (Q14676) Pfam (PF16770) Pfam (PF16589) In PDB | Homo sapiens (human) | Nuclear factor with BRCT domains 1 |
2 | C, D | phospho peptide | polymer | 5 | 603.5 | 2 | |||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
4 | water | water | 18.0 | 468 | Chemie (HOH) |
Sequence modifications
A, B: 1891 - 2089 (UniProt: Q14676)
PDB | External Database | Details |
---|---|---|
Gly 1890 | - | expression tag |
Asp 2067 | Thr 2067 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 44919.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 368.4 | |
All* | Total formula weight | 45287.9 |