3K05
The crystal structure of MDC1 BRCT T2067D in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1 |
| Chain | Residue |
| A | GLN2008 |
| A | GLU2063 |
| B | HOH69 |
| B | HOH186 |
| B | VAL1901 |
| B | ALA1903 |
| C | TYR142 |
| C | NH2143 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 2090 |
| Chain | Residue |
| B | HOH113 |
| B | HOH300 |
| B | HOH389 |
| B | ARG1943 |
| B | ARG1994 |
| B | SER2019 |
| B | GLY2022 |
| B | HOH78 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 1 |
| Chain | Residue |
| A | HOH71 |
| A | ARG1943 |
| A | ARG1994 |
| A | SER2019 |
| A | CYS2020 |
| A | GLY2022 |
| B | HOH37 |
| B | HOH289 |
| B | PRO2047 |
| B | SER2050 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 2091 |
| Chain | Residue |
| B | HOH82 |
| B | HOH84 |
| B | HOH235 |
| B | HOH409 |
| B | PHE1897 |
| B | GLY1899 |
| B | VAL1900 |
| B | LYS1936 |
| C | GLN140 |
| D | SEP139 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 156 |
| Details | Domain: {"description":"BRCT 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00033","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 182 |
| Details | Domain: {"description":"BRCT 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00033","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
