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3JTC

Importance of Mg2+ in the Ca2+-Dependent Folding of the gamma-Carboxyglutamic Acid Domains of Vitamin K-Dependent clotting and anticlotting Proteins

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BEndothelial protein C receptorpolymer19322046.62UniProt (Q9UNN8)
Pfam (PF16497)
In PDB
HOMO SAPIENS (human)Endothelial cell protein C receptor, Activated protein C receptor, APC receptor
2C, DVitamin K-dependent protein Cpolymer334359.42UniProt (P04070)
Pfam (PF00594)
In PDB
HOMO SAPIENS (human)Autoprothrombin IIA, Anticoagulant protein C, Blood coagulation factor XIV, Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide
3A, B2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.26Chemie (NAG)
4A, BPHOSPHATIDYLETHANOLAMINEnon-polymer734.02Chemie (PTY)
5C, DMAGNESIUM IONnon-polymer24.34Chemie (MG)
6C, DCALCIUM IONnon-polymer40.110Chemie (CA)
7waterwater18.0407Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight52811.9
Non-Polymers*Number of molecules22
Total formula weight3293.3
All*Total formula weight56105.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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