3JBQ

Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L, l	IgG1-kappa 2E8 light chain	polymer	214	23541.0	2		Mus musculus (mouse)
2	H, h	IgG1-kappa 2E8 heavy chain	polymer	220	23781.5	2		Mus musculus (mouse)
3	B, F	phosphodiesterase 5/6 chimera catalytic domain	polymer	330	38282.1	2	Pfam (PF00233) UniProt (by SIFTS) (Q28156) UniProt (by SIFTS) (P16586) In PDB	Bos taurus (bovine)	cGMP-specific 3',5'-cyclic phosphodiesterase, cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' chimera
4	D, X	phosphodiesterase 6 gamma subunit inhibitory peptide	polymer	18	2185.4	2	UniProt (P04972) In PDB	Bos taurus (bovine)	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma
5	C, G	GafB domain of phosphodiesterase 2A	polymer	185	20671.4	2	Pfam (PF01590) UniProt (by SIFTS) (P14099) In PDB	Bos taurus (bovine)	cGMP-dependent 3',5'-cyclic phosphodiesterase
6	1, 2	GafA domain of cone phosphodiesterase 6C	polymer	186	21554.8	2	Pfam (PF01590) UniProt (by SIFTS) (P52731) In PDB	Bos taurus (bovine)	cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	260032.5
All*	Total formula weight	260032.5

*Water molecules are not included.