3JBQ
Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, I (L, l) | IgG1-kappa 2E8 light chain | polymer | 214 | 23541.0 | 2 | Mus musculus (mouse) | ||
| 2 | B, J (H, h) | IgG1-kappa 2E8 heavy chain | polymer | 220 | 23781.5 | 2 | Mus musculus (mouse) | ||
| 3 | C, F (B, F) | phosphodiesterase 5/6 chimera catalytic domain | polymer | 330 | 38282.1 | 2 | Pfam (PF00233) UniProt (by SIFTS) (Q28156) UniProt (by SIFTS) (P16586) | Bos taurus (bovine) | cGMP-specific 3',5'-cyclic phosphodiesterase, cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' chimera |
| 4 | D, G (D, X) | phosphodiesterase 6 gamma subunit inhibitory peptide | polymer | 18 | 2185.4 | 2 | UniProt (P04972) | Bos taurus (bovine) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma |
| 5 | E, H (C, G) | GafB domain of phosphodiesterase 2A | polymer | 185 | 20671.4 | 2 | Pfam (PF01590) UniProt (by SIFTS) (P14099) | Bos taurus (bovine) | cGMP-dependent 3',5'-cyclic phosphodiesterase |
| 6 | K, L (1, 2) | GafA domain of cone phosphodiesterase 6C | polymer | 186 | 21554.8 | 2 | Pfam (PF01590) UniProt (by SIFTS) (P52731) | Bos taurus (bovine) | cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 260032.5 | |
| All* | Total formula weight | 260032.5 |
