3JBQ
Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| D | 0007601 | biological_process | visual perception |
| D | 0030553 | molecular_function | cGMP binding |
| F | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| F | 0007165 | biological_process | signal transduction |
| F | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| X | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| X | 0007601 | biological_process | visual perception |
| X | 0030553 | molecular_function | cGMP binding |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGvnNsY |
| Chain | Residue | Details |
| B | HIS653-TYR664 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YYCNAGH |
| Chain | Residue | Details |
| H | TYR90-HIS96 | |
| L | TYR192-HIS198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q922S4 |
| Chain | Residue | Details |
| C | SER431 | |
| G | THR499 | |
| C | ASP446 | |
| C | ILE465 | |
| C | TYR488 | |
| C | THR499 | |
| G | SER431 | |
| G | ASP446 | |
| G | ILE465 | |
| G | TYR488 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:O76074 |
| Chain | Residue | Details |
| B | HIS617 | |
| B | HIS653 | |
| B | ASP654 | |
| B | ASP764 | |
| F | HIS617 | |
| F | HIS653 | |
| F | ASP654 | |
| F | ASP764 |
