3JAB
Domain organization and conformational plasticity of the G protein effector, PDE6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, M) | GafA domain of cone phosphodiesterase 6C | polymer | 180 | 20725.9 | 2 | UniProt (by SIFTS) (A0A0M3KKT0) | Bos taurus (bovine) | cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' |
| 2 | C, D (B, N) | GafB domain of phosphodiesterase 2A | polymer | 185 | 20671.4 | 2 | Pfam (PF01590) UniProt (by SIFTS) (P14099) | Bos taurus (bovine) | cGMP-dependent 3',5'-cyclic phosphodiesterase |
| 3 | E, G (C, O) | phosphodiesterase 5/6 chimera catalytic domain | polymer | 330 | 38282.1 | 2 | Pfam (PF00233) UniProt (by SIFTS) (Q28156) UniProt (by SIFTS) (P16586) | Bos taurus (bovine) | cGMP-specific 3',5'-cyclic phosphodiesterase, cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' chimera |
| 4 | F, H (D, P) | phosphodiesterase 6 gamma subunit inhibitory peptide | polymer | 18 | 2185.4 | 2 | UniProt (P04972) | Bos taurus (bovine) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma |
| 5 | I, K (L, R) | IgG1-kappa 2E8 light chain | polymer | 214 | 23541.0 | 2 | Mus musculus (mouse) | ||
| 6 | J, L (H, Q) | IgG1-kappa 2E8 heavy chain | polymer | 221 | 23878.6 | 2 | Mus musculus (mouse) | ||
| 7 | M, N, O, P (C, O) | 3-ISOBUTYL-1-METHYLXANTHINE | non-polymer | 222.2 | 4 | Chemie (IBM) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 258568.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 889.0 | |
| All* | Total formula weight | 259457.9 |
