3J98
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Vesicle-fusing ATPase | polymer | 747 | 82907.4 | 6 | UniProt (P18708) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) Pfam (PF21964) In PDB | Cricetulus griseus (Chinese hamster) | N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, N-ethylmaleimide sensitive factor |
2 | H, I, J, G | Alpha-soluble NSF attachment protein | polymer | 297 | 33377.8 | 4 | UniProt (P54921) In PDB | Rattus norvegicus (rat) | SNAP-alpha, N-ethylmaleimide-sensitive factor attachment protein alpha, alpha-SNAP |
3 | K | Vesicle-associated membrane protein 2 | polymer | 63 | 7231.1 | 1 | UniProt (P63045) Pfam (PF00957) In PDB | Rattus norvegicus (rat) | VAMP-2, Synaptobrevin-2 |
4 | L | Syntaxin-1A | polymer | 67 | 7838.0 | 1 | UniProt (P32851) Pfam (PF05739) In PDB | Rattus norvegicus (rat) | Neuron-specific antigen HPC-1, Synaptotagmin-associated 35 kDa protein, P35A |
5 | M | Synaptosomal-associated protein 25 | polymer | 188 | 21256.9 | 1 | Pfam (PF00835) UniProt (by SIFTS) (P60881) In PDB | Rattus norvegicus (rat) | SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein |
Sequence modifications
A, B, C, D, E, F: 1 - 744 (UniProt: P18708)
H, I, J, G: 1 - 295 (UniProt: P54921)
K: 28 - 89 (UniProt: P63045)
L: 191 - 256 (UniProt: P32851)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ala -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 27 | - | expression tag |
PDB | External Database | Details |
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Met 190 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 13 |
Total formula weight | 667281.6 | |
All* | Total formula weight | 667281.6 |