Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3J98

Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000149	molecular_function	SNARE binding
A	0001921	biological_process	positive regulation of receptor recycling
A	0003689	molecular_function	DNA clamp loader activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005795	cellular_component	Golgi stack
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006338	biological_process	chromatin remodeling
A	0006813	biological_process	potassium ion transport
A	0006886	biological_process	intracellular protein transport
A	0006891	biological_process	intra-Golgi vesicle-mediated transport
A	0015031	biological_process	protein transport
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0017075	molecular_function	syntaxin-1 binding
A	0019901	molecular_function	protein kinase binding
A	0019905	molecular_function	syntaxin binding
A	0030165	molecular_function	PDZ domain binding
A	0030496	cellular_component	midbody
A	0035255	molecular_function	ionotropic glutamate receptor binding
A	0035494	biological_process	SNARE complex disassembly
A	0042802	molecular_function	identical protein binding
A	0043001	biological_process	Golgi to plasma membrane protein transport
A	0044877	molecular_function	protein-containing complex binding
A	0045732	biological_process	positive regulation of protein catabolic process
A	0046872	molecular_function	metal ion binding
A	0061775	molecular_function	cohesin loader activity
A	0140545	molecular_function	ATP-dependent protein disaggregase activity
A	0140584	molecular_function	chromatin extrusion motor activity
A	0140588	biological_process	chromatin looping
A	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
A	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
B	0000149	molecular_function	SNARE binding
B	0001921	biological_process	positive regulation of receptor recycling
B	0003689	molecular_function	DNA clamp loader activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005794	cellular_component	Golgi apparatus
B	0005795	cellular_component	Golgi stack
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006338	biological_process	chromatin remodeling
B	0006813	biological_process	potassium ion transport
B	0006886	biological_process	intracellular protein transport
B	0006891	biological_process	intra-Golgi vesicle-mediated transport
B	0015031	biological_process	protein transport
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0017075	molecular_function	syntaxin-1 binding
B	0019901	molecular_function	protein kinase binding
B	0019905	molecular_function	syntaxin binding
B	0030165	molecular_function	PDZ domain binding
B	0030496	cellular_component	midbody
B	0035255	molecular_function	ionotropic glutamate receptor binding
B	0035494	biological_process	SNARE complex disassembly
B	0042802	molecular_function	identical protein binding
B	0043001	biological_process	Golgi to plasma membrane protein transport
B	0044877	molecular_function	protein-containing complex binding
B	0045732	biological_process	positive regulation of protein catabolic process
B	0046872	molecular_function	metal ion binding
B	0061775	molecular_function	cohesin loader activity
B	0140545	molecular_function	ATP-dependent protein disaggregase activity
B	0140584	molecular_function	chromatin extrusion motor activity
B	0140588	biological_process	chromatin looping
B	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
B	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
C	0000149	molecular_function	SNARE binding
C	0001921	biological_process	positive regulation of receptor recycling
C	0003689	molecular_function	DNA clamp loader activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005794	cellular_component	Golgi apparatus
C	0005795	cellular_component	Golgi stack
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006338	biological_process	chromatin remodeling
C	0006813	biological_process	potassium ion transport
C	0006886	biological_process	intracellular protein transport
C	0006891	biological_process	intra-Golgi vesicle-mediated transport
C	0015031	biological_process	protein transport
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0017075	molecular_function	syntaxin-1 binding
C	0019901	molecular_function	protein kinase binding
C	0019905	molecular_function	syntaxin binding
C	0030165	molecular_function	PDZ domain binding
C	0030496	cellular_component	midbody
C	0035255	molecular_function	ionotropic glutamate receptor binding
C	0035494	biological_process	SNARE complex disassembly
C	0042802	molecular_function	identical protein binding
C	0043001	biological_process	Golgi to plasma membrane protein transport
C	0044877	molecular_function	protein-containing complex binding
C	0045732	biological_process	positive regulation of protein catabolic process
C	0046872	molecular_function	metal ion binding
C	0061775	molecular_function	cohesin loader activity
C	0140545	molecular_function	ATP-dependent protein disaggregase activity
C	0140584	molecular_function	chromatin extrusion motor activity
C	0140588	biological_process	chromatin looping
C	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
C	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
D	0000149	molecular_function	SNARE binding
D	0001921	biological_process	positive regulation of receptor recycling
D	0003689	molecular_function	DNA clamp loader activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005794	cellular_component	Golgi apparatus
D	0005795	cellular_component	Golgi stack
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006338	biological_process	chromatin remodeling
D	0006813	biological_process	potassium ion transport
D	0006886	biological_process	intracellular protein transport
D	0006891	biological_process	intra-Golgi vesicle-mediated transport
D	0015031	biological_process	protein transport
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0017075	molecular_function	syntaxin-1 binding
D	0019901	molecular_function	protein kinase binding
D	0019905	molecular_function	syntaxin binding
D	0030165	molecular_function	PDZ domain binding
D	0030496	cellular_component	midbody
D	0035255	molecular_function	ionotropic glutamate receptor binding
D	0035494	biological_process	SNARE complex disassembly
D	0042802	molecular_function	identical protein binding
D	0043001	biological_process	Golgi to plasma membrane protein transport
D	0044877	molecular_function	protein-containing complex binding
D	0045732	biological_process	positive regulation of protein catabolic process
D	0046872	molecular_function	metal ion binding
D	0061775	molecular_function	cohesin loader activity
D	0140545	molecular_function	ATP-dependent protein disaggregase activity
D	0140584	molecular_function	chromatin extrusion motor activity
D	0140588	biological_process	chromatin looping
D	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
D	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
E	0000149	molecular_function	SNARE binding
E	0001921	biological_process	positive regulation of receptor recycling
E	0003689	molecular_function	DNA clamp loader activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005794	cellular_component	Golgi apparatus
E	0005795	cellular_component	Golgi stack
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006338	biological_process	chromatin remodeling
E	0006813	biological_process	potassium ion transport
E	0006886	biological_process	intracellular protein transport
E	0006891	biological_process	intra-Golgi vesicle-mediated transport
E	0015031	biological_process	protein transport
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0017075	molecular_function	syntaxin-1 binding
E	0019901	molecular_function	protein kinase binding
E	0019905	molecular_function	syntaxin binding
E	0030165	molecular_function	PDZ domain binding
E	0030496	cellular_component	midbody
E	0035255	molecular_function	ionotropic glutamate receptor binding
E	0035494	biological_process	SNARE complex disassembly
E	0042802	molecular_function	identical protein binding
E	0043001	biological_process	Golgi to plasma membrane protein transport
E	0044877	molecular_function	protein-containing complex binding
E	0045732	biological_process	positive regulation of protein catabolic process
E	0046872	molecular_function	metal ion binding
E	0061775	molecular_function	cohesin loader activity
E	0140545	molecular_function	ATP-dependent protein disaggregase activity
E	0140584	molecular_function	chromatin extrusion motor activity
E	0140588	biological_process	chromatin looping
E	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
E	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
F	0000149	molecular_function	SNARE binding
F	0001921	biological_process	positive regulation of receptor recycling
F	0003689	molecular_function	DNA clamp loader activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005794	cellular_component	Golgi apparatus
F	0005795	cellular_component	Golgi stack
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006338	biological_process	chromatin remodeling
F	0006813	biological_process	potassium ion transport
F	0006886	biological_process	intracellular protein transport
F	0006891	biological_process	intra-Golgi vesicle-mediated transport
F	0015031	biological_process	protein transport
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0017075	molecular_function	syntaxin-1 binding
F	0019901	molecular_function	protein kinase binding
F	0019905	molecular_function	syntaxin binding
F	0030165	molecular_function	PDZ domain binding
F	0030496	cellular_component	midbody
F	0035255	molecular_function	ionotropic glutamate receptor binding
F	0035494	biological_process	SNARE complex disassembly
F	0042802	molecular_function	identical protein binding
F	0043001	biological_process	Golgi to plasma membrane protein transport
F	0044877	molecular_function	protein-containing complex binding
F	0045732	biological_process	positive regulation of protein catabolic process
F	0046872	molecular_function	metal ion binding
F	0061775	molecular_function	cohesin loader activity
F	0140545	molecular_function	ATP-dependent protein disaggregase activity
F	0140584	molecular_function	chromatin extrusion motor activity
F	0140588	biological_process	chromatin looping
F	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
F	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
G	0000149	molecular_function	SNARE binding
G	0005483	molecular_function	soluble NSF attachment protein activity
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0006886	biological_process	intracellular protein transport
G	0007420	biological_process	brain development
G	0010807	biological_process	regulation of synaptic vesicle priming
G	0015031	biological_process	protein transport
G	0016082	biological_process	synaptic vesicle priming
G	0016192	biological_process	vesicle-mediated transport
G	0019905	molecular_function	syntaxin binding
G	0030182	biological_process	neuron differentiation
G	0031594	cellular_component	neuromuscular junction
G	0032781	biological_process	positive regulation of ATP-dependent activity
G	0032984	biological_process	protein-containing complex disassembly
G	0035249	biological_process	synaptic transmission, glutamatergic
G	0035494	biological_process	SNARE complex disassembly
G	0043195	cellular_component	terminal bouton
G	0044877	molecular_function	protein-containing complex binding
G	0045176	biological_process	apical protein localization
G	0048787	cellular_component	presynaptic active zone membrane
G	0061025	biological_process	membrane fusion
G	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
G	0098793	cellular_component	presynapse
G	0098794	cellular_component	postsynapse
G	0098978	cellular_component	glutamatergic synapse
H	0000149	molecular_function	SNARE binding
H	0005483	molecular_function	soluble NSF attachment protein activity
H	0005515	molecular_function	protein binding
H	0005886	cellular_component	plasma membrane
H	0006886	biological_process	intracellular protein transport
H	0007420	biological_process	brain development
H	0010807	biological_process	regulation of synaptic vesicle priming
H	0015031	biological_process	protein transport
H	0016082	biological_process	synaptic vesicle priming
H	0016192	biological_process	vesicle-mediated transport
H	0019905	molecular_function	syntaxin binding
H	0030182	biological_process	neuron differentiation
H	0031594	cellular_component	neuromuscular junction
H	0032781	biological_process	positive regulation of ATP-dependent activity
H	0032984	biological_process	protein-containing complex disassembly
H	0035249	biological_process	synaptic transmission, glutamatergic
H	0035494	biological_process	SNARE complex disassembly
H	0043195	cellular_component	terminal bouton
H	0044877	molecular_function	protein-containing complex binding
H	0045176	biological_process	apical protein localization
H	0048787	cellular_component	presynaptic active zone membrane
H	0061025	biological_process	membrane fusion
H	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
H	0098793	cellular_component	presynapse
H	0098794	cellular_component	postsynapse
H	0098978	cellular_component	glutamatergic synapse
I	0000149	molecular_function	SNARE binding
I	0005483	molecular_function	soluble NSF attachment protein activity
I	0005515	molecular_function	protein binding
I	0005886	cellular_component	plasma membrane
I	0006886	biological_process	intracellular protein transport
I	0007420	biological_process	brain development
I	0010807	biological_process	regulation of synaptic vesicle priming
I	0015031	biological_process	protein transport
I	0016082	biological_process	synaptic vesicle priming
I	0016192	biological_process	vesicle-mediated transport
I	0019905	molecular_function	syntaxin binding
I	0030182	biological_process	neuron differentiation
I	0031594	cellular_component	neuromuscular junction
I	0032781	biological_process	positive regulation of ATP-dependent activity
I	0032984	biological_process	protein-containing complex disassembly
I	0035249	biological_process	synaptic transmission, glutamatergic
I	0035494	biological_process	SNARE complex disassembly
I	0043195	cellular_component	terminal bouton
I	0044877	molecular_function	protein-containing complex binding
I	0045176	biological_process	apical protein localization
I	0048787	cellular_component	presynaptic active zone membrane
I	0061025	biological_process	membrane fusion
I	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
I	0098793	cellular_component	presynapse
I	0098794	cellular_component	postsynapse
I	0098978	cellular_component	glutamatergic synapse
J	0000149	molecular_function	SNARE binding
J	0005483	molecular_function	soluble NSF attachment protein activity
J	0005515	molecular_function	protein binding
J	0005886	cellular_component	plasma membrane
J	0006886	biological_process	intracellular protein transport
J	0007420	biological_process	brain development
J	0010807	biological_process	regulation of synaptic vesicle priming
J	0015031	biological_process	protein transport
J	0016082	biological_process	synaptic vesicle priming
J	0016192	biological_process	vesicle-mediated transport
J	0019905	molecular_function	syntaxin binding
J	0030182	biological_process	neuron differentiation
J	0031594	cellular_component	neuromuscular junction
J	0032781	biological_process	positive regulation of ATP-dependent activity
J	0032984	biological_process	protein-containing complex disassembly
J	0035249	biological_process	synaptic transmission, glutamatergic
J	0035494	biological_process	SNARE complex disassembly
J	0043195	cellular_component	terminal bouton
J	0044877	molecular_function	protein-containing complex binding
J	0045176	biological_process	apical protein localization
J	0048787	cellular_component	presynaptic active zone membrane
J	0061025	biological_process	membrane fusion
J	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
J	0098793	cellular_component	presynapse
J	0098794	cellular_component	postsynapse
J	0098978	cellular_component	glutamatergic synapse
K	0016020	cellular_component	membrane
K	0016192	biological_process	vesicle-mediated transport
L	0005484	molecular_function	SNAP receptor activity
L	0006886	biological_process	intracellular protein transport
L	0016020	cellular_component	membrane
L	0016192	biological_process	vesicle-mediated transport
M	0000149	molecular_function	SNARE binding
M	0001917	cellular_component	photoreceptor inner segment
M	0005249	molecular_function	voltage-gated potassium channel activity
M	0005484	molecular_function	SNAP receptor activity
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005768	cellular_component	endosome
M	0005802	cellular_component	trans-Golgi network
M	0005856	cellular_component	cytoskeleton
M	0005886	cellular_component	plasma membrane
M	0005938	cellular_component	cell cortex
M	0006887	biological_process	exocytosis
M	0007269	biological_process	neurotransmitter secretion
M	0007409	biological_process	axonogenesis
M	0007616	biological_process	long-term memory
M	0007626	biological_process	locomotory behavior
M	0008021	cellular_component	synaptic vesicle
M	0008076	cellular_component	voltage-gated potassium channel complex
M	0008289	molecular_function	lipid binding
M	0008306	biological_process	associative learning
M	0010975	biological_process	regulation of neuron projection development
M	0015629	cellular_component	actin cytoskeleton
M	0016020	cellular_component	membrane
M	0016079	biological_process	synaptic vesicle exocytosis
M	0016082	biological_process	synaptic vesicle priming
M	0016197	biological_process	endosomal transport
M	0017022	molecular_function	myosin binding
M	0017075	molecular_function	syntaxin-1 binding
M	0019904	molecular_function	protein domain specific binding
M	0030027	cellular_component	lamellipodium
M	0030175	cellular_component	filopodium
M	0030182	biological_process	neuron differentiation
M	0030424	cellular_component	axon
M	0030426	cellular_component	growth cone
M	0031083	cellular_component	BLOC-1 complex
M	0031201	cellular_component	SNARE complex
M	0031629	biological_process	synaptic vesicle fusion to presynaptic active zone membrane
M	0031982	cellular_component	vesicle
M	0032024	biological_process	positive regulation of insulin secretion
M	0035493	biological_process	SNARE complex assembly
M	0036477	cellular_component	somatodendritic compartment
M	0042734	cellular_component	presynaptic membrane
M	0043005	cellular_component	neuron projection
M	0043025	cellular_component	neuronal cell body
M	0043195	cellular_component	terminal bouton
M	0044295	cellular_component	axonal growth cone
M	0044325	molecular_function	transmembrane transporter binding
M	0045202	cellular_component	synapse
M	0046887	biological_process	positive regulation of hormone secretion
M	0048306	molecular_function	calcium-dependent protein binding
M	0048471	cellular_component	perinuclear region of cytoplasm
M	0048791	biological_process	calcium ion-regulated exocytosis of neurotransmitter
M	0051963	biological_process	regulation of synapse assembly
M	0060291	biological_process	long-term synaptic potentiation
M	0070032	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
M	0070033	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
M	0070044	cellular_component	synaptobrevin 2-SNAP-25-syntaxin-1a complex
M	0070201	biological_process	regulation of establishment of protein localization
M	0071805	biological_process	potassium ion transmembrane transport
M	0097470	cellular_component	ribbon synapse
M	0098793	cellular_component	presynapse
M	0098794	cellular_component	postsynapse
M	0098888	cellular_component	extrinsic component of presynaptic membrane
M	0098967	biological_process	exocytic insertion of neurotransmitter receptor to postsynaptic membrane
M	0098978	cellular_component	glutamatergic synapse
M	0099525	biological_process	presynaptic dense core vesicle exocytosis
M	0099590	biological_process	neurotransmitter receptor internalization

Functional Information from PROSITE/UniProt

site_id	PS00417
Number of Residues	20
Details	SYNAPTOBREVIN Synaptobrevin signature. NVDKVlERdqKLSeLdDRAD

Chain	Residue	Details
K	ASN49-ASP68

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. IlVIgMTNrpdlIDeALl.R

Chain	Residue	Details
A	ILE367-ARG385

site_id	PS00914
Number of Residues	40
Details	SYNTAXIN Syntaxin / epimorphin family signature. RhseIikLEnsIrELhdMFmdMamlVesQGemIDrIEyn.V

Chain	Residue	Details
L	ARG198-VAL237

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: (Microbial infection) Cleavage; by C.botulinum neurotoxin type E (BoNT/E) => ECO:0000269\|PubMed:8243676, ECO:0000269\|PubMed:8294407, ECO:0000305\|PubMed:8103915

Chain	Residue	Details
M	ARG180
E	PRO545
F	ASN505
F	PRO545
I	MET1
J	MET1
G	MET1
C	ASN505
C	PRO545
D	ASN505
D	PRO545
E	ASN505

site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: (Microbial infection) Cleavage; by C.botulinum neurotoxin type A (BoNT/A, botA) => ECO:0000269\|PubMed:8243676, ECO:0000269\|PubMed:8294407, ECO:0000305\|PubMed:8103915

Chain	Residue	Details
M	GLN197
I	SER26
L	LYS253
L	LYS256
E	THR550
F	THR550

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by PKC and PKA => ECO:0000269\|PubMed:12459461

Chain	Residue	Details
M	THR138
H	SER195
I	SER29
I	SER195
J	SER29
J	SER195
G	SER29
G	SER195

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P60879

Chain	Residue	Details
M	SER154
B	SER207
C	SER207
D	SER207
E	SER207
F	SER207

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKC => ECO:0000269\|PubMed:12459461

Chain	Residue	Details
M	SER187
B	TYR259
C	TYR259
D	TYR259
E	TYR259
F	TYR259

site_id	SWS_FT_FI6
Number of Residues	4
Details	LIPID: S-palmitoyl cysteine => ECO:0000250\|UniProtKB:P60879

Chain	Residue	Details
M	CYS85
M	CYS88
M	CYS90
M	CYS92
E	SER569
F	SER569

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 642

Chain	Residue	Details
A	LYS549	electrostatic stabiliser
A	THR550	electrostatic stabiliser
A	ASP603	electrostatic stabiliser
A	ASP604	proton acceptor
A	LYS631	electrostatic stabiliser
A	LYS708	electrostatic stabiliser

site_id	MCSA2
Number of Residues	6
Details	M-CSA 642

Chain	Residue	Details
B	LYS549	electrostatic stabiliser
B	THR550	electrostatic stabiliser
B	ASP603	electrostatic stabiliser
B	ASP604	proton acceptor
B	LYS631	electrostatic stabiliser
B	LYS708	electrostatic stabiliser

site_id	MCSA3
Number of Residues	6
Details	M-CSA 642

Chain	Residue	Details
C	LYS549	electrostatic stabiliser
C	THR550	electrostatic stabiliser
C	ASP603	electrostatic stabiliser
C	ASP604	proton acceptor
C	LYS631	electrostatic stabiliser
C	LYS708	electrostatic stabiliser

site_id	MCSA4
Number of Residues	6
Details	M-CSA 642

Chain	Residue	Details
D	LYS549	electrostatic stabiliser
D	THR550	electrostatic stabiliser
D	ASP603	electrostatic stabiliser
D	ASP604	proton acceptor
D	LYS631	electrostatic stabiliser
D	LYS708	electrostatic stabiliser

site_id	MCSA5
Number of Residues	6
Details	M-CSA 642

Chain	Residue	Details
E	LYS549	electrostatic stabiliser
E	THR550	electrostatic stabiliser
E	ASP603	electrostatic stabiliser
E	ASP604	proton acceptor
E	LYS631	electrostatic stabiliser
E	LYS708	electrostatic stabiliser

site_id	MCSA6
Number of Residues	6
Details	M-CSA 642

Chain	Residue	Details
F	LYS549	electrostatic stabiliser
F	THR550	electrostatic stabiliser
F	ASP603	electrostatic stabiliser
F	ASP604	proton acceptor
F	LYS631	electrostatic stabiliser
F	LYS708	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)