Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy


Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
D, B, E, GTransient receptor potential cation channel subfamily V member 1polymer59868242.24
UniProt (O35433)
Pfam (PF00023)
Pfam (PF00520)
Rattus norvegicus (rat)@PDBjTrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Vanilloid receptor type 1-like
A, C, F, HDouble-knot toxinpolymer312656.34
Chilobrachys jingzhao (Chinese earth tiger tarantula)DkTx

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains8
Total molecular weight283593.7
Non-Polymers*Number of molecules0
Total molecular weight0.0
All*Total molecular weight283593.7
*Water molecules are not included.
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