3J5Q
Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (D, B, E, G) | Transient receptor potential cation channel subfamily V member 1 | polymer | 628 | 70795.2 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Norway rat) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like |
| 2 | E, F, G, H (A, C, F, H) | Kappa-theraphotoxin-Cg1a 1 | polymer | 31 | 3433.0 | 4 | UniProt (P0C247) Pfam (PF07740) | Chilobrachys guangxiensis | double-knot toxin |
Sequence modifications
D, B, E, G: 111 - 719 (UniProt: O35433)
D, B, E, G: 721 - 762 (PDB: 3J5Q)
| PDB | External Database | Details |
|---|---|---|
| - | Asn 604 | deletion |
| - | Asn 605 | deletion |
| - | Ser 606 | deletion |
| - | Leu 607 | deletion |
| - | Pro 608 | deletion |
| - | Met 609 | deletion |
| - | Glu 610 | deletion |
| - | Ser 611 | deletion |
| - | Thr 612 | deletion |
| - | Pro 613 | deletion |
| - | His 614 | deletion |
| - | Lys 615 | deletion |
| - | Cys 616 | deletion |
| - | Arg 617 | deletion |
| - | Gly 618 | deletion |
| - | Ser 619 | deletion |
| - | Ala 620 | deletion |
| - | Cys 621 | deletion |
| - | Lys 622 | deletion |
| - | Pro 623 | deletion |
| - | Gly 624 | deletion |
| - | Asn 625 | deletion |
| - | Ser 626 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 296912.9 | |
| All* | Total formula weight | 296912.9 |
