3IUX
Crystal structure of human MDM2 in complex with a potent miniature protein inhibitor (18-residues)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | E3 ubiquitin-protein ligase Mdm2 | polymer | 85 | 10044.9 | 2 | UniProt (Q00987) Pfam (PF02201) | p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2 | |
| 2 | B, D (B, D) | miniature protein inhibitor | polymer | 18 | 2216.6 | 2 | |||
| 3 | E, F, G (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | H, I, J (A, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 24523.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 283.5 | |
| All* | Total formula weight | 24806.5 |
