3IUX
Crystal structure of human MDM2 in complex with a potent miniature protein inhibitor (18-residues)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| C | 0005634 | cellular_component | nucleus |
| C | 0043066 | biological_process | negative regulation of apoptotic process |
| C | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 1 |
| Chain | Residue |
| A | LYS45 |
| A | ASP46 |
| A | THR47 |
| A | HOH143 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 2 |
| Chain | Residue |
| A | ASN79 |
| A | HIS96 |
| A | HOH133 |
| A | HOH157 |
| A | HOH177 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 3 |
| Chain | Residue |
| A | ALA43 |
| A | GLN44 |
| A | LYS45 |
| D | ARG14 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 1 |
| Chain | Residue |
| C | ASN79 |
| C | HIS96 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 110 |
| Chain | Residue |
| A | HOH18 |
| A | PRO32 |
| A | LEU33 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 110 |
| Chain | Residue |
| C | ASP46 |
| C | THR47 |
