3ITU
hPDE2A catalytic domain complexed with IBMX
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | cGMP-dependent 3',5'-cyclic phosphodiesterase | polymer | 345 | 40225.1 | 4 | UniProt (O00408) Pfam (PF00233) In PDB | Homo sapiens (human) | Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE |
2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
4 | A, B, C, D | 3-ISOBUTYL-1-METHYLXANTHINE | non-polymer | 222.2 | 4 | Chemie (IBM) | |||
5 | water | water | 18.0 | 1777 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 579 - 919 (UniProt: O00408)
PDB | External Database | Details |
---|---|---|
Gly 575 | - | expression tag |
Ser 576 | - | expression tag |
Ala 577 | - | expression tag |
Met 578 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 160900.4 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1247.8 | |
All* | Total formula weight | 162148.2 |