3ISW
Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Filamin-A | polymer | 99 | 10177.2 | 2 | UniProt (P21333) Pfam (PF00630) In PDB | Homo sapiens (human) | Alpha-filamin, Filamin-1, Endothelial actin-binding protein, Actin-binding protein 280, ABP-280, Non-muscle filamin |
2 | C | Cystic fibrosis transmembrane conductance regulator | polymer | 18 | 2009.3 | 1 | UniProt (P13569) In PDB | CFTR, Channel conductance-controlling ATPase, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7 | |
3 | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B: 2236 - 2329 (UniProt: P21333)
C: 5 - 22 (UniProt: P13569)
PDB | External Database | Details |
---|---|---|
Gly 2231 | - | expression tag |
Ala 2232 | - | expression tag |
Met 2233 | - | expression tag |
Pro 2234 | - | expression tag |
Asp 2235 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 21 | Arg 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 22363.7 | |
All* | Total formula weight | 22363.7 |