3INQ
Crystal structure of BCL-XL in complex with W1191542
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bcl-2-like protein 1 | polymer | 158 | 17918.0 | 2 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | Bcl2-L-1, Apoptosis regulator Bcl-X |
| 2 | A, B | 4-[4-(biphenyl-3-ylmethyl)piperazin-1-yl]-N-{[4-({(1R)-3-(dimethylamino)-1-[(phenylsulfanyl)methyl]propyl}amino)-3-nitrophenyl]sulfonyl}benzamide | non-polymer | 779.0 | 2 | Chemie (X0J) | |||
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 4 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 26 (UniProt: Q07817)
A, B: 83 - 209 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35835.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2276.2 | |
| All* | Total formula weight | 38112.1 |
