Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0042981 | biological_process | regulation of apoptotic process |
B | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE X0J A 210 |
Chain | Residue |
A | ALA93 |
A | GLY138 |
A | VAL141 |
A | PHE191 |
A | TYR195 |
A | EDO217 |
B | ARG102 |
A | GLU96 |
A | PHE97 |
A | TYR101 |
A | LEU108 |
A | GLU129 |
A | ARG132 |
A | ASN136 |
A | TRP137 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 211 |
Chain | Residue |
A | VAL192 |
A | GLU193 |
A | LEU194 |
A | HOH310 |
B | TYR101 |
B | X0J210 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 212 |
Chain | Residue |
A | SER14 |
A | MET83 |
A | LYS87 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 213 |
Chain | Residue |
A | GLN88 |
A | ARG91 |
A | EDO214 |
B | ASP11 |
B | ARG91 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 214 |
Chain | Residue |
A | ASP11 |
A | ARG91 |
A | EDO213 |
B | GLN88 |
B | ARG91 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 215 |
Chain | Residue |
A | GLN160 |
A | HOH237 |
B | TRP24 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 216 |
Chain | Residue |
A | LYS16 |
A | GLN19 |
A | LYS20 |
A | HOH231 |
B | GLU98 |
site_id | AC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 217 |
Chain | Residue |
A | ASN136 |
A | ARG139 |
A | X0J210 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 218 |
Chain | Residue |
A | ARG100 |
A | TYR101 |
A | ARG102 |
A | ARG103 |
A | ALA104 |
site_id | BC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO A 219 |
Chain | Residue |
A | HOH71 |
A | ARG165 |
site_id | BC2 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE X0J B 210 |
Chain | Residue |
A | GLU193 |
A | EDO211 |
B | GLU96 |
B | PHE97 |
B | TYR101 |
B | LEU108 |
B | ASN136 |
B | TRP137 |
B | GLY138 |
B | VAL141 |
B | PHE146 |
B | PHE191 |
B | TYR195 |
site_id | BC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO B 212 |
Chain | Residue |
B | GLY21 |
B | EDO213 |
site_id | BC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO B 213 |
Chain | Residue |
B | GLY196 |
B | EDO212 |
Functional Information from PROSITE/UniProt
site_id | PS01080 |
Number of Residues | 19 |
Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
Chain | Residue | Details |
A | LEU130-GLY148 | |
site_id | PS01258 |
Number of Residues | 12 |
Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
Chain | Residue | Details |
A | TRP181-VAL192 | |
site_id | PS01259 |
Number of Residues | 15 |
Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
Chain | Residue | Details |
A | VAL86-ARG100 | |
site_id | PS01260 |
Number of Residues | 21 |
Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
Chain | Residue | Details |
A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | SITE: Cleavage; by caspase-1 |
Chain | Residue | Details |
A | GLY117 | |
B | GLY117 | |
Chain | Residue | Details |
A | PHE105 | |
B | PHE105 | |
Chain | Residue | Details |
A | THR118 | |
B | THR118 | |