3IN5

Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion

Replaces:  3HED

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA polymerase kappa	polymer	508	58038.3	2	UniProt (Q9UBT6) Pfam (PF00817) Pfam (PF11798) Pfam (PF11799)	Homo sapiens (human)	DINB protein, DINP
2	C, E (P, Q)	DNA (5'-D(*GP*G*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*(DOC))-3')	polymer	13	4065.7	2
3	D, F (T, U)	DNA (5'-D(*C*CP*TP*AP*(8OG)P*GP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3')	polymer	18	5404.5	2
4	G, J (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
5	H, I, K, L (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	M, N, O (A, B, U)	water	water		18.0	18	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	135016.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1111.6
All*	Total formula weight	136128.4

*Water molecules are not included.