3IK9

Human GST A1-1-GIMF with GSDHN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Glutathione S-transferase A1	polymer	222	25703.1	8	UniProt (P08263) Pfam (PF02798) Pfam (PF00043) In PDB	Homo sapiens (human)	GTH1, HA subunit 1, GST-epsilon, GSTA1-1, GST class-alpha member 1
2	A, B, C, D, E...	(S)-2-amino-5-((R)-1-(carboxymethylamino)-3-((3S,4R)-1,4-dihydroxynonan-3-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid	non-polymer		465.6	8	Chemie (BOB)
3		water	water		18.0	59	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 222 (UniProt: P08263)

PDB	External Database	Details
Gly 12	Ala 12	engineered mutation
Ile 107	Leu 107	engineered mutation
Met 108	Leu 108	engineered mutation
Phe 111	Val 111	engineered mutation
Pro 208	Met 208	engineered mutation
Ile 211	Lys 211	engineered mutation
Tyr 212	Ser 212	engineered mutation
Val 213	Leu 213	engineered mutation
Arg 214	Glu 214	engineered mutation
Thr 215	Glu 215	engineered mutation
Val 216	Ala 216	engineered mutation
Tyr 217	Arg 217	engineered mutation
Asn 218	Lys 218	engineered mutation
Pro 222	Phe 222	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	205624.9
Non-Polymers*	Number of molecules	8
	Total formula weight	3724.5
All*	Total formula weight	209349.4

*Water molecules are not included.