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3HY6

Structure of human MTHFS with ADP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
5-formyltetrahydrofolate cyclo-ligasepolymer20323289.71UniProt (P49914)
Pfam (PF01812)
Homo sapiens (human)5,10-methenyl-tetrahydrofolate synthetase, Methenyl-THF synthetase, MTHFS
2B, D, Q
(A)
NICKEL (II) IONnon-polymer58.73Chemie (NI)
3C, E, F, G, H...
(A)
MAGNESIUM IONnon-polymer24.312Chemie (MG)
4I
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
5L
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
6S
(A)
waterwater18.0147Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23289.7
Non-Polymers*Number of molecules17
Total formula weight989.9
All*Total formula weight24279.6
*Water molecules are not included.

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PDB entries from 2025-12-17

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