3HQP
Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with ATP, Oxalate and fructose 2,6 bisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Pyruvate kinase | polymer | 499 | 54467.9 | 16 | UniProt (Q27686) Pfam (PF00224) Pfam (PF02887) | Leishmania mexicana | PK |
| 2 | AB, BB, BD, CD, EA... (F, M, C, J, G...) | MAGNESIUM ION | non-polymer | 24.3 | 30 | Chemie (MG) | |||
| 3 | AD, CB, DA, DD, EC... (L, F, B, M, I...) | POTASSIUM ION | non-polymer | 39.1 | 32 | Chemie (K) | |||
| 4 | AA, DB, ED, HA, IC... (B, F, M, C, J...) | OXALATE ION | non-polymer | 88.0 | 15 | Chemie (OXL) | |||
| 5 | AC, BA, EB, FD, IA... (I, B, F, M, C...) | 2,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 16 | Chemie (FDP) | |||
| 6 | BC, CA, FB, GD, JA... (I, B, F, M, C...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 15 | Chemie (ATP) | |||
| 7 | CC, DC, LC, NB, QD... (I, J, G, O, E) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 8 | AE, BE, CE, DE, EE... (A, B, C, D, E...) | water | water | 18.0 | 4100 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 0 - 498 (UniProt: Q27686)
| PDB | External Database | Details |
|---|---|---|
| Ser 382 | Gly 383 | SEE REMARK 999 |
| Tyr 389 | Ser 390 | SEE REMARK 999 |
| Arg 404 | Ala 405 | SEE REMARK 999 |
| Ser 405 | Gly 406 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 871486.9 | |
| Non-Polymers* | Number of molecules | 114 |
| Total formula weight | 16902.7 | |
| All* | Total formula weight | 888389.7 |
