3HO5
Crystal structure of Hedgehog-interacting protein (HHIP) and Sonic hedgehog (SHH) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hedgehog-interacting protein | polymer | 481 | 54087.2 | 2 | UniProt (Q96QV1) Pfam (PF07995) Pfam (PF07974) | Homo sapiens (human) | HHIP, HIP |
| 2 | C (H) | Sonic hedgehog protein | polymer | 169 | 19122.5 | 1 | UniProt (Q15465) Pfam (PF01085) | Homo sapiens (human) | SHH, HHG-1, Sonic hedgehog protein N-product, Sonic hedgehog protein C-product |
| 3 | D, E (A, H) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F, G (H) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
A, B: 193 - 667 (UniProt: Q96QV1)
| PDB | External Database | Details |
|---|---|---|
| His 668 | - | expression tag |
| His 669 | - | expression tag |
| His 670 | - | expression tag |
| His 671 | - | expression tag |
| His 672 | - | expression tag |
| His 673 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 127297.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 211.0 | |
| All* | Total formula weight | 127507.9 |
