3HNB
Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (M) | Coagulation factor VIII | polymer | 159 | 18029.6 | 1 | UniProt (P00451) Pfam (PF00754) | Homo sapiens (human) | recombine factor VIII, Procoagulant component, Antihemophilic factor, AHF |
| 2 | B (M) | (2R)-1-(2,4-dichlorophenoxy)-3-[(2E)-2-imino-3-(2-piperidin-1-ylethyl)-2,3-dihydro-1H-benzimidazol-1-yl]propan-2-ol | non-polymer | 463.4 | 1 | Chemie (768) | |||
| 3 | C (M) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18029.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 463.4 | |
| All* | Total formula weight | 18493.0 |
