3HNB
Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 768 M 1 |
| Chain | Residue |
| M | LYS2258 |
| M | GLN2311 |
| M | SER2312 |
| M | TRP2313 |
| M | HIS2315 |
Functional Information from PROSITE/UniProt
| site_id | PS01285 |
| Number of Residues | 30 |
| Details | FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. AWrpqvnnpke......WLqVDfqktmkVtgVtTQG |
| Chain | Residue | Details |
| M | ALA2218-GLY2247 |
| site_id | PS01286 |
| Number of Residues | 17 |
| Details | FA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Pqswvhqia..LRmEVlGC |
| Chain | Residue | Details |
| M | PRO2310-CYS2326 |
