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3HL2

The crystal structure of the human SepSecS-tRNASec complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
O-phosphoseryl-tRNA(Sec) selenium transferasepolymer50155801.24UniProt (Q9HD40)
Pfam (PF05889)
Homo sapiens (human)Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase, Sep-tRNA:Sec-tRNA synthase, SepSecS, UGA suppressor tRNA-associated protein, tRNA(Ser/Sec)-associated antigenic protein, Liver-pancreas antigen, LP, Soluble liver antigen, SLA, SLA/LP autoantigen, SLA-p35
2E
(E)
tRNASecpolymer9028908.11Homo sapiens (human)
3F, I, L, N
(A, B, C, D)
(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATEnon-polymer233.24Chemie (PLR)
4G, H, M
(A, C)
Monothiophosphatenon-polymer114.13Chemie (TS6)
5J, K, O, P
(B, D)
PHOSPHOSERINEnon-polymer185.14Chemie (SEP)
6Q, R, S, T, U
(A, B, C, D, E)
waterwater18.0288Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight252112.9
Non-Polymers*Number of molecules11
Total formula weight2015.1
All*Total formula weight254128.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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