3HEI
Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... | Ephrin type-A receptor 2 | polymer | 174 | 19913.6 | 8 | UniProt (P29317) Pfam (PF01404) In PDB | Homo sapiens (human) | Tyrosine-protein kinase receptor ECK, Epithelial cell kinase |
| 2 | B, D, F, H, J... | Ephrin-A1 | polymer | 132 | 15884.8 | 8 | UniProt (P20827) Pfam (PF00812) In PDB | Homo sapiens (human) | EPH-related receptor tyrosine kinase ligand 1, LERK-1, Immediate early response protein B61, Tumor necrosis factor, alpha-induced protein 4 |
| 3 | water | water | 18.0 | 2756 | Chemie (HOH) |
Sequence modifications
B, D, F, H, J, L, N, P: 18 - 147 (UniProt: P20827)
| PDB | External Database | Details |
|---|---|---|
| Lys 148 | - | expression tag |
| Ile 149 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 286387.3 | |
| All* | Total formula weight | 286387.3 |
