3H4K
Crystal structure of the wild type Thioredoxin glutatione reductase from Schistosoma mansoni in complex with auranofin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thioredoxin glutathione reductase | polymer | 598 | 65108.0 | 1 | UniProt (Q962Y6) Pfam (PF00462) Pfam (PF07992) Pfam (PF02852) | Schistosoma mansoni (Blood fluke) | |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C, D, E (A) | GOLD ION | non-polymer | 197.0 | 3 | Chemie (AU) | |||
| 4 | F (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 5 | G (A) | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 6 | H, I (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 7 | J (A) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 1 - 598 (UniProt: Q962Y6)
| PDB | External Database | Details |
|---|---|---|
| Sec 597 | Unk 597 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65108.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2111.3 | |
| All* | Total formula weight | 67219.4 |
