3GYF
Human DHFR with Z-isomer in Orthorhombic lattice
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 187 | 21480.7 | 1 | UniProt (P00374) Pfam (PF00186) | Homo sapiens (Human) | |
| 2 | B (A) | 5-[(1Z)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine | non-polymer | 296.3 | 1 | Chemie (51P) | |||
| 3 | C (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | G (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21480.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1329.9 | |
| All* | Total formula weight | 22810.7 |
