3GXP
Crystal structure of acid-alpha-galactosidase A complexed with galactose at pH 4.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alpha-galactosidase A | polymer | 398 | 45394.5 | 2 | UniProt (P06280) Pfam (PF16499) Pfam (PF17450) | Homo sapiens (Human) | Alpha-D-galactoside galactohydrolase, Alpha-D-galactosidase A, Melibiase |
| 2 | C (C) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 3 | D, E, F, G (D, E, F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 4 | H, M, N, O (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | I, R (A, B) | alpha-D-galactopyranose | non-polymer | 180.2 | 2 | Chemie (GLA) | |||
| 6 | J (A) | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 1 | Chemie (TAM) | |||
| 7 | K, L (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 8 | P, Q (B) | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
| 9 | S, T (A, B) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90789.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2284.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1710.5 | |
| All* | Total formula weight | 94783.7 |
