3GDH
Methyltransferase domain of human Trimethylguanosine Synthase 1 (TGS1) bound to m7GTP and adenosyl-homocysteine (active form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Trimethylguanosine synthase homolog | polymer | 241 | 26743.8 | 3 | UniProt (Q96RS0) Pfam (PF09445) | Homo sapiens (Human) | Nuclear receptor coactivator 6-interacting protein, PRIP-interacting protein with methyltransferase motif, PIPMT, PIMT, CLL-associated antigen KW-2, Hepatocellular carcinoma-associated antigen 137 |
| 2 | D, H, K (A, B, C) | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 538.2 | 3 | Chemie (MGP) | |||
| 3 | E, I, L (A, B, C) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 3 | Chemie (SAH) | |||
| 4 | F, G, J, M (A, B, C) | R-1,2-PROPANEDIOL | non-polymer | 76.1 | 4 | Chemie (PGR) | |||
| 5 | N (C) | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 1 | Chemie (PGO) | |||
| 6 | O, P, Q (A, B, C) | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A, B, C: 618 - 853 (UniProt: Q96RS0)
| PDB | External Database | Details |
|---|---|---|
| Gly 613 | - | expression tag |
| Pro 614 | - | expression tag |
| Leu 615 | - | expression tag |
| Gly 616 | - | expression tag |
| Ser 617 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 80231.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3148.3 | |
| All* | Total formula weight | 83379.7 |
