3G33

Crystal structure of CDK4/cyclin D3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Cell division protein kinase 4	polymer	308	34184.3	2	UniProt (P11802) Pfam (PF00069)	Homo sapiens (human)	Cyclin-dependent kinase 4, PSK-J3
2	B, D (B, D)	CCND3 protein	polymer	306	34056.3	2	UniProt (Q6FG62) Pfam (PF00134) Pfam (PF02984) UniProt (by SIFTS) (P30281)	Homo sapiens (human)	Cyclin D3, isoform CRA_b

Sequence modifications

A, C: 6 - 308 (UniProt: P11802)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Leu 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag

B, D: 1 - 292 (UniProt: Q6FG62)

PDB	External Database	Details
Met -13	-	expression tag
Asp -12	-	expression tag
Tyr -11	-	expression tag
Lys -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Lys -5	-	expression tag
Ser -4	-	expression tag
Pro -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	136481.1
All*	Total formula weight	136481.1

*Water molecules are not included.