3FVK
Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with 8-deoxy-neodysiherbaine A in space group P1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor, ionotropic kainate 1 | polymer | 256 | 29093.4 | 2 | UniProt (P39086) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (Human) | Glutamate receptor 5, GluR-5, GluR5, Excitatory amino acid receptor 3, EAA3 |
| 2 | C, D, E, F, G... (A, B) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 3 | H, M (A, B) | (2R,3aR,6S,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-6-hydroxy-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid | non-polymer | 275.3 | 2 | Chemie (8DX) | |||
| 4 | I, N, O (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | P, Q (A, B) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
A, B: 415 - 529 (UniProt: P39086)
A, B: 652 - 790 (UniProt: P39086)
A, B: 652 - 790 (UniProt: P39086)
| PDB | External Database | Details |
|---|---|---|
| Gly 600 | - | linker |
| Thr 601 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58186.9 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1575.5 | |
| All* | Total formula weight | 59762.3 |
