3FSL
Crystal structure of tyrosine aminotransferase tripple mutant (P181Q,R183G,A321K) from Escherichia coli at 2.35 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Aromatic-amino-acid aminotransferase | polymer | 397 | 43568.6 | 6 | UniProt (P04693) Pfam (PF00155) | Escherichia coli K-12 | tyrosine aminotransferase, AROAT, ARAT |
| 2 | G, H, I, J, K... (A, B, C, D, E...) | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE | non-polymer | 233.2 | 6 | Chemie (PLR) | |||
| 3 | M (A) | water | water | 18.0 | 879 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 5 - 409 (UniProt: P04693)
| PDB | External Database | Details |
|---|---|---|
| Gln 181 | Pro 171 | engineered mutation |
| Gly 183 | Arg 173 | engineered mutation |
| Lys 321 | Ala 310 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 261411.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1398.9 | |
| All* | Total formula weight | 262810.7 |
