3FNV
Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CDGSH iron sulfur domain-containing protein 2 | polymer | 83 | 9490.0 | 2 | UniProt (Q8N5K1) Pfam (PF09360) | Homo sapiens (Human) | Endoplasmic reticulum intermembrane small protein, MitoNEET-related 1 protein, Miner1 |
| 2 | C, D (A, B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B: 57 - 135 (UniProt: Q8N5K1)
| PDB | External Database | Details |
|---|---|---|
| Gly 53 | - | expression tag |
| Ser 54 | - | expression tag |
| His 55 | - | expression tag |
| Met 56 | - | expression tag |
| Ser 92 | Cys 92 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18980.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 351.6 | |
| All* | Total formula weight | 19331.7 |
