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3FNV

Crystal Structure of Miner1: The Redox-active 2Fe-2S Protein Causative in Wolfram Syndrome 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0010506biological_processregulation of autophagy
A0043231cellular_componentintracellular membrane-bounded organelle
A0051537molecular_function2 iron, 2 sulfur cluster binding
B0010506biological_processregulation of autophagy
B0043231cellular_componentintracellular membrane-bounded organelle
B0051537molecular_function2 iron, 2 sulfur cluster binding
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE FES A 200
ChainResidue
ACYS99
AARG100
ACYS101
ACYS110
AASP111
AGLY112
ASER113
AHIS114

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE FES B 200
ChainResidue
BARG100
BCYS101
BCYS110
BASP111
BSER113
BHIS114
BCYS99

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues148
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
APRO61-VAL135
BPRO61-VAL135

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING:
ChainResidueDetails
ACYS99
ACYS101
ACYS110
AHIS114
BCYS99
BCYS101
BCYS110
BHIS114

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PDB entries from 2024-10-30

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