3FJL
Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase, Dihydroorotate oxidase |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (710) PubChem (8965) PubChem (643976) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (23585816) PubChem (51435500) PubChem (51435503) PubChem (15559251) | |||
| 3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E, F (A) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 6 | G (A) | (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide | non-polymer | 322.4 | 1 | Chemie (CJH) PubChem (76211845) PubChem (54727985) | |||
| 7 | H (A) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39856.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1151.0 | |
| All* | Total formula weight | 41007.5 |
