3FGU

Catalytic complex of Human Glucokinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Glucokinase	polymer	470	52996.2	1	UniProt (P35557) Pfam (PF00349) Pfam (PF03727)	Homo sapiens (Human)	Pancreatic Glucokinase, Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D
2	B (A)	beta-D-glucopyranose	non-polymer		180.2	1	Chemie (BGC)
3	C (A)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
4	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	E (A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
6	F (A)	water	water		18.0	192	Chemie (HOH)

Sequence modifications

A: 12 - 465 (UniProt: P35557)

PDB	External Database	Details
Met -4	-	expression tag
Gly -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
Glu 4	-	expression tag
Asn 5	-	expression tag
Leu 6	-	expression tag
Tyr 7	-	expression tag
Phe 8	-	expression tag
Gln 9	-	expression tag
Gly 10	-	expression tag
Met 11	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	52996.2
Non-Polymers*	Number of molecules	4
	Total formula weight	749.8
All*	Total formula weight	53745.9

*Water molecules are not included.