3FF7

Structure of NK cell receptor KLRG1 bound to E-cadherin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Epithelial cadherin	polymer	100	11124.6	2	UniProt (P12830) Pfam (PF00028) In PDB	Homo sapiens (human)	E-cadherin, Cadherin-1, Uvomorulin, CAM 120/80, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3
2	C, D	Killer cell lectin-like receptor subfamily G member 1	polymer	112	12972.6	2	UniProt (Q96E93) Pfam (PF00059) In PDB	Homo sapiens (human)	Mast cell function-associated antigen, MAFA-like receptor, ITIM-containing receptor MAFA-L, C-type lectin domain family 15 member A
3	D	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
4		water	water		18.0	309	Chemie (HOH)

Sequence modifications

A, B: 1 - 99 (UniProt: P12830)

PDB	External Database	Details
Met 0	-	expression tag
Leu 9	Cys 163	engineered mutation

C, D: 75 - 186 (UniProt: Q96E93)

PDB	External Database	Details
Ser 131	Cys 131	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	48194.4
Non-Polymers*	Number of molecules	1
	Total formula weight	60.1
All*	Total formula weight	48254.5

*Water molecules are not included.