3FER

Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Filamin-B	polymer	262	30539.9	4	UniProt (O75369) Pfam (PF00307)	Homo sapiens (human)	FLN-B, Beta-filamin, Actin-binding-like protein, Thyroid autoantigen, Truncated actin-binding protein, Truncated ABP, ABP-280 homolog, ABP-278, Filamin 3, Filamin homolog 1, Fh1
2	E, F (B, C)	ACETIC ACID	non-polymer		60.1	2	Chemie (ACY)
3	G, H, I, J (A, B, C, D)	water	water		18.0	153	Chemie (HOH)

Sequence modifications

A, B, C, D: 11 - 262 (UniProt: O75369)

PDB	External Database	Details
Mse 1	-	expression tag
Gly 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Ser 9	-	expression tag
His 10	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	122159.7
Non-Polymers*	Number of molecules	2
	Total formula weight	120.1
All*	Total formula weight	122279.8

*Water molecules are not included.