3F6U
Crystal structure of human Activated Protein C (APC) complexed with PPACK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | Vitamin K-dependent protein C heavy chain | polymer | 240 | 26965.8 | 1 | UniProt (P04070) Pfam (PF00089) In PDB | Homo sapiens | Autoprothrombin IIA, Anticoagulant protein C, Blood coagulation factor XIV |
| 2 | L | Vitamin K-dependent protein C light chain | polymer | 98 | 10802.4 | 1 | UniProt (P04070) Pfam (PF14670) In PDB | Homo sapiens | Autoprothrombin IIA, Anticoagulant protein C, Blood coagulation factor XIV |
| 3 | H | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 1 | BIRD (PRD_000020) Chemie (0G6) | PPACK | ||
| 4 | H | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | H | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37768.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 517.1 | |
| All* | Total formula weight | 38285.3 |
